指标1:估计葡萄糖处理率
(estimated Glucose Disposal Rate, eGDR)
计算公式:eGDR=21.158-(0.09×WC)-(3.407×高血压)-(0.551×HbA1c)[WC(cm),高血压(是=1/否=0),HbA1c(%)]
指标简介:eGDR是一种用于评估胰岛素敏感性和葡萄糖代谢能力的综合指标。它通过腰围、高血压状态和糖化血红蛋白水平的组合,提供了一个简单、实用的评估方法,用于预测个体的胰岛素抵抗状态。研究显示,eGDR被验证与传统评估IR的金标准——高胰岛素-正葡萄糖钳夹技术高度相关,并且eGDR水平不受肾排泄功能的影响。
案例文章

标题:Estimated glucose disposal rate for predicting cardiovascular events and mortality in patients with non-diabetic chronic kidney disease: a prospective cohort study
期刊:BMC Med(IF=7.0)
PMID:39334214

标题:Association of estimated glucose disposal rate with metabolic syndrome prevalence and mortality risks: a population-based study
期刊:Cardiovasc Diabetol(IF=8.5)
PMID:39844166

标题:Gender differences in the association between insulin resistance assessed by estimated glucose disposal rate and the risk of all-cause and cardiovascular deaths in adults without diabetes
期刊:Diabetes Res Clin Pract(IF=6.1)
PMID:39709110
指标2:应激高血糖比值
(stress hyperglycemia ratio, SHR)
计算公式:SHR=[FPG(mmol/L)]/[1.59×HbA1c(%)−2.59]
指标简介:SHR是一种综合评估急性应激状态下高血糖程度的指标,通过结合空腹血糖(FPG)和糖化血红蛋白(HbA1c),反映患者当前血糖水平相对于其长期血糖控制状态的偏离程度。相较于单独使用FPG和HbA1c,SHR可以精准识别应激性高血糖,单独使用FPG可能无法区分应激性高血糖与糖尿病相关高血糖,HbA1c反映长期血糖水平,对应激性高血糖的敏感性不足。
案例文章

标题:The prognostic value of the stress hyperglycemia ratio for all-cause and cardiovascular mortality in patients with diabetes or prediabetes: insights from NHANES 2005-2018
期刊:Cardiovasc Diabetol(IF=8.5)
PMID:38419029

标题:The prognostic significance of stress hyperglycemia ratio in evaluating all-cause and cardiovascular mortality risk among individuals across stages 0-3 of cardiovascular-kidney-metabolic syndrome: evidence from two cohort studies
期刊:Cardiovasc Diabetol(IF=8.5)
PMID:40128747

标题:The association between stress-induced hyperglycemia ratio and cardiovascular events as well as all-cause mortality in patients with chronic kidney disease and diabetic nephropathy
期刊:Cardiovasc Diabetol(IF=8.5)
PMID:39915833
指标3:CALLY指数
(C-reactive protein-albumin-lymphocyte index,CALLY index)
计算公式:CALLY指数=albumin(g/L)×lymphocytes(10⁹/L)÷[CRP(mg/L)×10]
指标简介:CALLY指数是一种新型复合炎症-营养-免疫指标,通过整合C反应蛋白、白蛋白和淋巴细胞计数,综合评估全身炎症状态、营养状况及免疫功能。白蛋白反映营养状态与肝脏合成功能;淋巴细胞计数反应免疫功能;CRP是急性期炎症标志物。CALLY指数通过比值标准化,消除单一指标的局限性,同时捕捉炎症负荷、营养储备及免疫功能,提供更全面的生理状态评估。CALLY指数降低与重症患者死亡率、感染复发风险及治疗抵抗显著相关。
案例文章

标题:Negative association of C-reactive protein-albumin-lymphocyte index (CALLY index) with all-cause and cause-specific mortality in patients with cancer: results from NHANES 1999-2018
期刊:BMC Cancer(IF=3.4)
PMID:39639229

标题:The association between C-reactive protein-albumin-lymphocyte index and depression in adults with type 2 diabetes mellitus: A cross-sectional study from NHANES
期刊:Psychoneuroendocrinology(IF=3.4)
PMID:40138851

标题:The relationship between CALLY index and stroke in hypertensive patients: insights from NHANES
期刊:Front Nutr(IF=4.0)
PMID:40491586
指标4:体重调整腰指数
(Weight-Adjusted Waist Index,WWI)
计算公式:WWI=腰围(cm)/体重(kg)1/2
指标简介:体重调整腰指数(WWI)是一种结合腰围(WC)与体重(Weight)的复合指标,计算简单,且更精准反映内脏脂肪堆积与代谢风险。相比传统指标(如BMI或单纯腰围),WWI能更好地识别内脏肥胖/中心性肥胖。WWI升高与胰岛素抵抗、高血压、血脂异常及2型糖尿病风险显著相关,且独立于BMI。
案例文章

标题:Association between Weight-Adjusted Waist Index and depressive symptoms: A nationally representative cross-sectional study from NHANES 2005 to 2018
期刊:J Affect Disord(IF=4.9)
PMID:38220117

标题:Relationship between weight-adjusted-waist index and all-cause and cardiovascular mortality in individuals with type 2 diabetes
期刊:Diabetes Obes Metab(IF=5.4)
PMID:39295078

标题:Association of the weight-adjusted waist index with hypertension in the context of predictive, preventive, and personalized medicine
期刊:The EPMA journal(IF=6.0)
PMID:39239106
指标5:非高密度脂蛋白胆固醇与高密度脂蛋白胆固醇比值
(Non-HDL-C to HDL-C Ratio, NHHR)
计算公式:NHHR=Non-HDL-C/HDL-C.Non-HDL-C=total cholesterol(TC)−HDL-C
指标简介:NHHR是评估脂蛋白代谢与动脉粥样硬化风险的关键指标。非高密度脂蛋白胆固醇(non-HDL-C):指血液中除高密度脂蛋白胆固醇(HDL-C)以外的其他脂蛋白所含胆固醇的总和。高密度脂蛋白胆固醇(HDL-C):具有逆向转运胆固醇、抗炎及抗氧化作用,可减少动脉粥样硬化风险。NHHR通过整合致动脉粥样硬化脂蛋白(non-HDL-C)与抗动脉粥样硬化脂蛋白(HDL-C)的平衡关系,更全面反映心血管疾病风险,尤其在传统血脂指标(如LDL-C)无法充分评估风险的情况下具有重要价值。
案例文章

标题:The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and risk of depression among US adults: A cross-sectional NHANES study
期刊:J Affect Disord(IF=4.9)
PMID:37838268

标题:The association of the non-HDL-cholesterol to HDL-cholesterol ratio (NHHR) with obstructive sleep apnea among adults aged ≥ 40 years: results from NHANES 2015-2018
期刊:BMC Public Health(IF=3.5)
PMID:40442689
指标6:血红蛋白与红细胞分布宽度比值
(Hemoglobin-to-Red Blood Cell Distribution Width Ratio, Hb/RDW,HRR)
计算公式:HRR=血红蛋白(g/dL)/红细胞分布宽度
指标简介:Hb/RDW比值通过整合携氧能力(Hb)与红细胞形态异质性(RDW),动态评估贫血病因、炎症状态及预后风险,尤其在慢性病、心血管疾病及肿瘤领域具有独特价值。血红蛋白浓度代表红细胞的携氧能力,而RDW反映红细胞大小的变化。血红蛋白/RDW比率提供了对红细胞功能的更细致的理解。
案例文章

标题:Hemoglobin-to-red blood cell distribution width ratio is negatively associated with stroke: a cross-sectional study from NHANES
期刊:Sci Rep(IF=3.8)
PMID:39543321

标题:Exploring the hemoglobin-to-red blood cell distribution width ratio (HRR) to peripheral arterial disease nexus: a comprehensive analysis of NHANES data from 1999 to 2004
期刊:Front Pharmacol(IF=4.4)
PMID:39911849





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